General Cell Based Assays
Revvity Health Sciences Inc HTRF Human Phospho-PLC-γ2 (Tyr1217) Detection Kit, 50,000 Assay Points
HTRF Human Phospho-PLC-γ2 (Tyr1217) Detection Kit, 50,000 Assay Points
ABclonal Technology Phospho-CRMP2/DPYSL2-T514 Rabbit pAb
This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimers disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Sigma Aldrich Fine Chemicals Biosciences Indican Assay Kit sufficie
Indican (indoxyl sulfate) is a putrefaction product resulting from bacterial deconjugation of tryptophan in the small intestine. Indican is water soluble and excreted through urine. Increases in urine indican can indicate protein maldigestion or malabsortion or the overgrowth of gut anaerobic bacteria. Indican levels in urine can also increase in response to a high protein diet.
MOLECULAR DEPOT LLC Tricaprylin Triglyceride 200mg
Tricaprylin Triglyceride (200 mg) is a triester of glycerin and octanoic acid with a molecular weight of 470 69 g/mol It is supplied as a neat liquid For in vitro research use only Not for human or animal use
Cayman Chemical Glycogen phsphoylase InHBI 5mg
A cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM); blocks glucagon-induced hepatic glycogenolysis in vivo
Meso Scale Discovery U-PLEX Human MMP-1 ASY
The Meso Scale Discovery U-PLEX Human MMP-1 Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of MMP-1 in human serum plasma and cell culture supernatants It utilizes electrochemiluminescent detection technology and provides high sensitivity broad dynamic range and rapid results The assay requires 50 L or less sample volume and can be read on MSD instrument platforms It includes a 96-well plate pre-coated with capture antibodies detection antibodies and calibrators and controls needed to generate a standard curve and validate assay performance This product allows sensitive reproducible quantification of MMP-1 levels
ABclonal Technology LDH-B
This gene encodes the B subunit of lactate dehydrogenase enzyme which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD in a post-glycolysis process Alternatively spliced transcript variants have been found for this gene Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism and that this isoform is localized in the peroxisomes Mutations in this gene are associated with lactate dehydrogenase B deficiency Pseudogenes have been identified on chromosomes X 5 and 13
Eurofins Discoverx PATHHUNTER U2OS TRKA-P75 BIOAS
PathHunter U2OS TrkA-p75 Bioassay Kit, 200 dp (2 x 96-well).
Eurofins Discoverx InCELL Hunter eXpress CLK2 Kinase Binding Assay, 10pl Kit. (96-0057E15CP0L)
The InCELL Hunter eXpress CLK2 Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of CLK2 via detection of CLK2 levels. This product uses EFC technology. The cell line included overexpresses CLK2 target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx InCELL Hunter eXpress BTK Kinase Binding Assay, 10pl Kit. (96-0056E15CP0L)
The InCELL Hunter eXpress BTK Kinase Binding Assay provides an easy-to-use cell based assay to study small molecule drug candidates that engage with kinases. This kit assesses compound-engagement-based stabilization of BTK via detection of BTK levels. This product uses EFC technology. The cell line included overexpresses BTK target protein fused to ProLabel. In the absence of compound that binds and stabilizes the target, this protein is degraded and no EFC signal is produced. When compound engages and stabilizes the target, EA contained in the detection reagent produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.